Identify the correct statements about biomolecules.
A. Lipids are generally water soluble.
B. Proteins are polypeptides.
C. Polysaccharides are long chains of sugars.
D. Adenine and guanine are substituted pyrimidines.
E. Almost all enzymes are proteins.

Choose the correct answer from the options given below :

The correct set of statements is **B, C and E only**.

Statement A: “Lipids are generally water soluble.”
Lipids, such as fats, oils, phospholipids, and steroids, possess long hydrocarbon chains that are non‑polar. Non‑polar molecules do not interact favorably with polar water molecules, making lipids **hydrophobic** (water‑insoluble) in most cases. Therefore, statement A is false.

Statement B: “Proteins are polypeptides.”
A protein is a macromolecule composed of one or more **polypeptide chains**, each of which is a linear sequence of amino acids linked by peptide bonds. Hence, proteins are indeed polypeptides (or aggregates of them). Statement B is true.

Statement C: “Polysaccharides are long chains of sugars.”
Polysaccharides consist of many monosaccharide units joined together by glycosidic bonds, forming long carbohydrate polymers such as starch, glycogen, and cellulose. This matches the description in statement C, so it is true.

Statement D: “Adenine and guanine are substituted pyrimidines.”
Adenine and guanine belong to the **purine** family, which have a double‑ring structure. Pyrimidines (e.g., cytosine, thymine, uracil) have a single‑ring structure. Therefore, calling adenine and guanine “substituted pyrimidines” is incorrect. Statement D is false.

Statement E: “Almost all enzymes are proteins.”
The vast majority of catalytic enzymes in living organisms are proteins. While a few ribozymes (RNA enzymes) exist, they are exceptions. Consequently, statement E is true.

Summarizing the truth values:

A – False
B – True
C – True
D – False
E – True

The combination of the true statements is **B, C and E only**, which matches the provided correct answer.