If a double-stranded DNA has 15% of adenine, find out the percent of cytosine in the DNA?
Correct Answer :
35%
Solution :
The correct option is 35%.
According to Chargaff's rules of base pairing in a double-stranded DNA molecule, the total amount of purines is always equal to the total amount of pyrimidines. Specifically:
1. Adenine (A) pairs with Thymine (T), which means:
2. Guanine (G) pairs with Cytosine (C), which means:
The sum of all four nitrogenous bases in the DNA is 100%:
Given in the problem, Adenine (A) is equal to 15%.
Using Chargaff's rule:
Therefore, the combined percentage of Adenine and Thymine is:
Next, we find the remaining percentage for Guanine and Cytosine:
Since the percentage of Guanine is equal to the percentage of Cytosine, we divide the remaining percentage by 2:
Thus, the percentage of cytosine in the DNA is 35%.
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