If the letters of the word SYMPHONY are arranged in alphabetical order, how many letters will be located between the letter that is second from the left end and the letter that is second from the right end in this newly formed sequence?

To find the number of letters located between the letter that is second from the left end and the letter that is second from the right end, let us follow a step-by-step approach.

Step 1: Identify the letters of the given word.
The given word is SYMPHONY.
The letters present in this word are: S, Y, M, P, H, O, N, Y.

Step 2: Arrange the letters in alphabetical order.
Sorting the letters of SYMPHONY alphabetically gives:
H, M, N, O, P, S, Y, Y

Step 3: Identify the required letter positions in the newly formed sequence.
1. The letter that is second from the left end is M.
2. The letter that is second from the right end is Y (the first 'Y' from the right side).

Step 4: Count the letters located between these two positions.
The sequence between the second letter from the left (M) and the second letter from the right (Y) is:
H, [M], N, O, P, S, [Y], Y

The letters lying strictly between M and Y are: N, O, P, S.

Counting these letters, we get 4 letters in total.

Therefore, the correct answer is 4.