Match List I with List II

List I		List II
A	α –I antitrypsin	I	Cotton bollworm
B	Cry IAb	II	ADA deficiency
C	Cry IAc	III	Emphysema
D	Enzyme replacement therapy	IV	Corn borer

Choose the correct answer from the options given below:

To find the correct match between List I and List II, let us analyze each item individually based on established biological and medical concepts:

A. α-1 antitrypsin: α-1 antitrypsin is a protein used to treat emphysema (a chronic lung disease where the alveoli are damaged). Thus, A matches with III.

B. Cry IAb: The cryIAb gene from Bacillus thuringiensis controls corn borer infestations. Thus, B matches with IV.

C. Cry IAc: The cryIAc gene (along with cryIIAb) is used to control cotton bollworms. Thus, C matches with I.

D. Enzyme replacement therapy: Enzyme replacement therapy is a medical treatment used to treat certain genetic disorders, such as Adenosine Deaminase (ADA) deficiency, by replacing the deficient enzyme. Thus, D matches with II.

Combining all the correct matches, we get:
A - III
B - IV
C - I
D - II

Therefore, the correct option is A-III, B-IV, C-I, D-II.