Question Details

Persons with ‘AB’ blood group are called as “Universal recipients”. This is due to :

Options

A

Absence of antigens A and B on the surface of RBCs

B

Absence of antigens A and B in plasma

C

Presence of antibodies, anti-A and anti-B, on RBCs

D

Absence of antibodies, anti-A and anti-B, in plasma

Show Answer

Correct Answer :

Option D

Absence of antibodies, anti-A and anti-B, in plasma

Absence of antibodies, anti-A and anti-B, in plasma

Solution :

To understand why individuals with the AB blood group are called "Universal Recipients," we must examine the components of the ABO blood group system, which are determined by the presence or absence of specific antigens on the surface of red blood cells (RBCs) and antibodies in the plasma.

1. Antigens (on RBCs): Individuals with blood group AB have both Antigen A and Antigen B present on the surface of their red blood cells.
2. Antibodies (in Plasma): The immune system produces antibodies against antigens that are not present on its own red blood cells to prevent self-destruction. Since both A and B antigens are present on the RBCs of an AB individual, their plasma does not produce anti-A or anti-B antibodies. If these antibodies were present, they would attack the person's own red blood cells.

Because individuals with blood group AB lack both anti-A and anti-B antibodies in their plasma, they can receive red blood cells from any blood type (A, B, AB, or O) without triggering a major immune reaction (hemolysis) due to recipient antibodies. Therefore, they are referred to as universal recipients.

Thus, the correct option is Absence of antibodies, anti-A and anti-B, in plasma.

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