What are the potential drawbacks in adoption of the IVF method?

A. High fatality risk to mother 

B. Expensive instruments and reagents

C. Husband/wife necessary for being donors

D. Less adoption of orphans

F. Possibility that the early embryo does not survive

Choose the correct answer from the options given below:

In Vitro Fertilization (IVF) is an assisted reproductive technology (ART) where eggs are fertilized by sperm outside the body in a laboratory setting. While it has helped many couples conceive, there are several social, ethical, and economic drawbacks associated with its adoption. Let us analyze the given statements to identify these drawbacks:

A. High fatality risk to mother: This statement is incorrect. While IVF procedures carry some health risks (such as ovarian hyperstimulation syndrome or risks associated with multiple pregnancies), they do not carry a "high fatality risk" to the mother under modern medical standards.

B. Expensive instruments and reagents: This statement is correct. IVF requires highly specialized laboratory equipment, cleanroom environments, and expensive biochemical reagents and hormones, making the treatment highly expensive and less accessible to lower-income families.

C. Husband/wife necessary for being donors: This statement is incorrect. IVF allows the use of donor eggs, donor sperm, or donor embryos from third parties, so it is not strictly necessary for the husband or wife to be the biological donors.

D. Less adoption of orphans: This statement is correct. From a social perspective, the wide availability and preference for IVF and other assisted reproductive technologies often lead couples to prefer biological children, which can result in a decrease in the adoption rates of orphaned children.

F. Possibility that the early embryo does not survive: This statement is correct. During IVF, multiple embryos are typically cultured, and not all of them survive the cleavage or blastocyst stages in the lab, nor do all transferred embryos successfully implant in the uterus. The potential loss of early embryos is a significant medical and ethical concern.

Therefore, statements B, D, and F represent valid drawbacks to the adoption of the IVF method.

Thus, the correct option is B, D, F only.