What should come in place of the question mark (?) in the given series?
6 19 45 97 201 ?

The correct option is 409.

To find the missing number in the series, let us analyze the pattern between consecutive terms:
6, 19, 45, 97, 201, ?

Let's look at the relationship between each number and the next one:

1st term to 2nd term:
$$6\times 2+7=12+7=19$$

2nd term to 3rd term:
$$19\times 2+7=38+7=45$$

3rd term to 4th term:
$$45\times 2+7=90+7=97$$

4th term to 5th term:
$$97\times 2+7=194+7=201$$

Following the same pattern, we multiply the 5th term by 2 and add 7 to get the next term:

$$201\times 2+7=402+7=409$$

Thus, the number that should come in place of the question mark is 409.