When gene targetting involving gene amplification is attempted in an individual’s tissue to treat disease, it is known as :

When a medical approach tries to modify the genes in a patient’s own cells by increasing the copy number of a beneficial gene (gene amplification), the goal is to correct or compensate for a disease‑causing defect.

This strategy is called gene therapy because the treatment works by delivering genetic material into the patient’s tissue to produce a therapeutic effect.

Key points that identify it as gene therapy:

1. Targeting the genome – the method directly interacts with the DNA of the individual’s cells.

2. Gene amplification – adding extra copies of a functional gene increases the production of the desired protein.

3. Therapeutic intent – the purpose is to treat or alleviate a disease, not merely to diagnose, test safety, or appropriate genetic resources.

Therefore, the correct term for this approach is Gene therapy.