Question Details

Which is the "Only enzyme" that has "Capability" to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?

Options

A

DNA Ligase

B

DNase

C

DNA dependent DNA polymerase

D

DNA dependent RNA polymerase

Show Answer

Correct Answer :

Option D

DNA dependent RNA polymerase

DNA dependent RNA polymerase

Solution :

The correct answer is DNA dependent RNA polymerase.

In prokaryotic transcription, the entire process—initiation, elongation, and termination—is carried out by a single enzyme.

During initiation, the DNA‑dependent RNA polymerase binds to the promoter region of a gene, unwinds the DNA locally, and forms the transcription initiation complex.

Once the RNA strand is begun, the enzyme proceeds to the elongation phase, adding ribonucleotides to the growing RNA chain by synthesizing RNA complementary to the DNA template.

Finally, the enzyme recognizes specific terminator sequences or forms a hairpin structure in the nascent RNA, which triggers termination, releasing the RNA transcript and dissociating from the DNA.

Other enzymes listed (DNA ligase, DNase, DNA‑dependent DNA polymerase) are involved in DNA replication, repair, or degradation, but none can perform all three transcription steps. Only DNA‑dependent RNA polymerase possesses the full catalytic capability required for transcription in prokaryotes.

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