Directions: Rearrange the given sentences in a logical sequence to form a coherent paragraph, then answer the question below.

(A) He found that a high percentage of patients experienced functional loss before age 50.
(B) Recently, medical researchers identified a cellular protein linked to aggressive forms of Parkinson's.
(C) Parkinson’s is a progressive neurological disorder that gradually disrupts movement and motor control.
(D) Prompted by this discovery, Dr. Vance analyzed patient records from 40 major hospitals.
(E) These findings underscore the critical need for early diagnostic tools and targeted interventions.
(F) This ongoing physical decline is compounded by the reality that current medications merely address symptoms.

Which of the following sentences should be the SECOND sentence in the logical sequence?

The correct answer is F.

To find the logical sequence of the given sentences and identify the second sentence, we can trace the structural and thematic connections:
1. Sentence (C) establishes the topic by defining Parkinson’s disease as a progressive neurological disorder affecting movement and motor control, making it the ideal introductory sentence.
2. Sentence (F) naturally follows (C) because the phrase "This ongoing physical decline" directly references the progressive disruption of motor control described in sentence (C).
3. Sentence (B) introduces a new research finding regarding a cellular protein linked to Parkinson's.
4. Sentence (D) connects to sentence (B) via "Prompted by this discovery," detailing how Dr. Vance analyzed patient records.
5. Sentence (A) follows (D) by stating the results of Dr. Vance's hospital record analysis ("He found that...").
6. Sentence (E) concludes the paragraph by summarizing the impact of Dr. Vance's findings ("These findings underscore...").

The logical order of the entire paragraph is C – F – B – D – A – E.
Therefore, the SECOND sentence in the logical sequence is F.