Choose the word that is most nearly opposite in meaning to the specified word.

Concur

The correct option is Dissent.

Explanation:
The word Concur means to agree with an opinion, decision, or statement.
To find the word that is most nearly opposite in meaning (antonym), let's examine the definitions of all the options:

1. Agony: Extreme physical or mental suffering. This is unrelated to agreement.
2. Mourn: To feel or show deep sadness or grief. This is unrelated to agreement.
3. Dissent: To hold or express opinions that differ from those commonly or officially held; to disagree. This is the exact opposite of Concur.
4. Wrath: Extreme or intense anger. This is unrelated to agreement or disagreement.

Therefore, the word most nearly opposite in meaning to 'Concur' is Dissent.