Select the option that can replace the highlighted part of the sentence grammatically and contextually correctly. If no replacement is required,

select “No Replacement”. He do not understand the meaning of this word.

The correct answer is does not comprehend.

Let us analyze the grammar and context of the original sentence:
"He do not understand the meaning of this word."

1. Subject-Verb Agreement:
The subject of the sentence is "He", which is a third-person singular pronoun. In English grammar, a third-person singular subject requires the singular auxiliary verb "does" rather than the plural auxiliary verb "do". Therefore, "He do not" is grammatically incorrect and must be replaced with "He does not".

2. Vocabulary and Context:
The word "understand" means to perceive the intended meaning of something. The word "comprehend" is a synonym that means to grasp mentally or understand fully. Replacing "do not understand" with "does not comprehend" maintains the exact contextual meaning of the sentence while correcting the grammatical error. Thus, "does not comprehend" is the correct grammatical and contextual replacement.

3. Why the other options are incorrect:
- "do not understated": This option uses the incorrect auxiliary verb "do" for a singular subject, and "understated" is grammatically incorrect in this context.
- "is running": This changes the entire meaning of the sentence and makes no logical sense in the context of understanding a word.
- "understand": This does not resolve the negation or grammatical structure of the sentence.