Select the option that can replace the highlighted part of the sentence grammatically and contextually correctly. If no replacement is required,

select “No Replacement”. He do not understand the meaning of this word.

The correct answer is does not comprehend.

Step-by-step Explanation:

1. Analyze the original sentence:
The original sentence is: "He do not understand the meaning of this word."
The subject of the sentence is "He", which is a third-person singular pronoun.

2. Identify the grammatical error:
In English grammar, the auxiliary verb "do" must agree with the subject in number and person:
- For plural subjects and pronouns (I, we, you, they), we use "do".
- For third-person singular subjects and pronouns (he, she, it), we use "does".
Therefore, "He do not" is grammatically incorrect. It must be corrected to "He does not".

3. Evaluate the options:
- "does not comprehend": This option uses the correct third-person singular auxiliary verb "does" followed by the base form verb "comprehend" (which is a synonym of "understand"). This is grammatically correct and contextually fitting.
- "do not understated": This retains the incorrect subject-verb agreement ("He do") and uses the past tense/participle form "understated" incorrectly after the auxiliary verb.
- "is running": While grammatically correct, "He is running the meaning of this word" does not make any contextual sense.
- "understand": Substituting "do not understand" with "understand" gives "He understand...", which violates subject-verb agreement since a singular third-person subject requires "understands".
- "No replacement": Incorrect because the original sentence contains a subject-verb agreement error.

4. Conclusion:
The option "does not comprehend" perfectly corrects the subject-verb agreement error while preserving the original meaning of the sentence.